Rapid Diagnosis of Trisomy 13, 18, 21 and Sex Chomosomes Aneuploidies
Product Overview
The Aneufast™ QF-PCR Kit contains six multiplex marker sets of short tandem repeats (STRs) that can be used for amplification of selected microsatellites and the Amelogenin-SRY.
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This combination of markers allows the detection of aneuploidies involving chromosomes X, Y, 21, 18 and 13. Aneufast™ is intended to be used to amplify DNA extracted from fresh prenatal samples such as Amniotic Fluids, CVSs or fetal blood. It can also be used to analyse neonatal and adult blood or tissue samples.
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Two multiplex QF-PCR sets (S1and S2) are used to perform initial Aneuploidy Screening and the assays are designed to be analysed in a single electrophoresis; In addition, there are four chromosome- specific marker sets (M21, M13, M18 and MXY). They may be used as back-ups in case all the markers on S1 and S2 are non-informative (homozygous). However, they may also be applied individually for the diagnosis of trisomy 13, 18, 21 and sex chromosome aneuploidies, respectively.
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Copyright Aneufast™ QF-PCR 2006